Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Children: A Randomized Controlled Clinical Trial

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Compared with adults, children have higher metabolic needs, and the airway is more likely to collapse. Before tracheal intubation after anesthesia induction, the patient 's spontaneous breathing completely disappears. At this critical stage, the residual oxygen of the lung is consumed, resulting in hypoxemia and atelectasis. Therefore, it is necessary to explore the best oxygenation strategy during intubation. In addition, ultrasound has become a common equipment in the operating room. It has the advantages of portability, repeatability, and no radiation, and can provide strong support for the diagnosis of gastric distension.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 2
Maximum Age: 10
Healthy Volunteers: t
View:

• Age 2-10 years old;

• American Society of Anesthesiologists (ASA) Level I or II;

• Children with healthy lungs and hearts;

• Clear headed and able to cooperate with anesthesiologists for treatment.

Locations
Other Locations
China
Department of Anaesthesiology and Perioperative Medicine, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital
RECRUITING
Zhengzhou
Contact Information
Primary
KuangYu Zhao
844523078@qq.com
+8613251535857
Backup
Jun Zhou, PHD
zhoujun@zzu.edu.cn
+8613592582222
Time Frame
Start Date: 2023-12-04
Estimated Completion Date: 2025-05-01
Participants
Target number of participants: 48
Treatments
Experimental: Group HFNC
In the HFNC group, the mask ventilation was performed after the patient lost spontaneous breathing until the end-tidal oxygen concentration reached 90 %. The mask was removed and HFNC ( AIRVO2, Fisher Parker Medical Company, Auckland, New Zealand ) was used to record the patient 's safe apnea time. After the end of positive pressure ventilation, intubation or laryngeal mask placement was performed after the end-tidal oxygen concentration reached 90 % or more. During the intubation or placement of the laryngeal mask, the HFNC nasal catheter was kept in the patient 's nose for apnea oxygenation.
No_intervention: Group control
No intervention
Related Therapeutic Areas
Sponsors
Leads: Henan Provincial People's Hospital

This content was sourced from clinicaltrials.gov